Owned my 2003 Sequoia since 2003. Aside from brakes, tires and the usual maintenance (which is reasonable), I haven't had any big problems.
Cruising speed and long distance drives are a pleasure. All the bells and whistles on mine meant nothing except an iPod adaptor was needed. Still looks great today as it did new.
Like how Toyota sticks behind it's product no matter how many years pass.
Truly a nice SUV on a truck platform. It's so reliable.